Novel technology — Inhibitor-free genomic DNA for improved sensitivity in real-time PCR
Better PCR results through highly pure and intact genomic DNA
BioEcho’s EchoLUTION technology for extraction of genomic DNA combines a particular effective lysis with an outstandingly convenient and fast spin column purification.
The risk of chemical and physical DNA damage is minimized, e. g., by reduction of shearing of high molecular weight molecules: target nucleic acids remain untouched throughout the entire gentle, yet straightforward workflow.
Free of any inhibitors = more sensitive detection in real-time PCR
Inhibitors from the purification process such as chaotropic reagents like Guanidinium or ethanol and other organic solvents are often the reason for compromised PCR sensitivity or even drop-outs. EchoLUTION-purified DNA is completely free of contaminants and enzyme inhibitors and is highly suited for all downstream applications, particularly those that require high sensitivity.
Never bind-wash-elute again for
a good working PCR!
Relying on current bind-wash-elute technology, scientists often observe lowered sensitivity for enzyme-dependent analyses such as real-time PCR, caused by residual inhibiting molecules (e.g., ethanol or salt) carried over from the purification process which frequently comes in combination with low quantities of DNA.
In qPCR experiments that are based on limited starting material, EchoLUTION-extracted DNA easily outperforms results obtained with DNA purified using Silica-based bind-wash-elute technology.
Inhibitor-free DNA purification in just a single step and for every throughput!
The EchoLUTION DNA extraction method combines the novel TurboLyseTM lysis technology with a unique single-step purification process.
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